Robert G Sawyer Selected Research

linopristin drug combination flopristin

2/2010

NXL-103, a combination of flopristin and linopristin, for the potential treatment of bacterial infections including community-acquired pneumonia and MRSA.

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Robert G Sawyer Research Topics

Disease

78	Infections 01/2022 - 01/2002
22	Wounds and Injuries (Trauma) 12/2021 - 01/2002
20	Intraabdominal Infections 05/2018 - 01/2002
19	Critical Illness (Critically Ill) 12/2020 - 01/2004
15	Sepsis (Septicemia) 06/2021 - 08/2004
13	Surgical Wound Infection 09/2020 - 12/2008
8	Obesity 09/2016 - 09/2007
5	Fever (Fevers) 03/2021 - 10/2006
5	Coinfection 02/2016 - 04/2010
5	Ventilator-Associated Pneumonia 10/2014 - 12/2007
4	Septic Shock (Toxic Shock Syndrome) 09/2021 - 10/2013
4	Lung Diseases (Lung Disease) 01/2021 - 12/2007
4	Ileus 04/2016 - 07/2010
4	Leukocytosis (Pleocytosis) 04/2016 - 10/2006
4	Pneumonia (Pneumonitis) 10/2013 - 04/2003
4	Hemorrhage 04/2012 - 04/2011
3	Stroke (Strokes) 01/2021 - 06/2013
3	Thrombocytopenia (Thrombopenia) 12/2020 - 04/2011
3	Colitis 08/2017 - 10/2010
3	Body Weight (Weight, Body) 12/2015 - 10/2007
3	Morbid Obesity 10/2015 - 10/2007
3	Cross Infection (Nosocomial Infection) 10/2014 - 01/2002
2	COVID-19 01/2022 - 12/2020
2	Bacteremia 12/2021 - 08/2015
2	Heart Failure 01/2021 - 06/2013
2	Inflammation (Inflammations) 01/2019 - 05/2010
2	Peritonitis 09/2018 - 12/2012
2	Soft Tissue Infections 10/2015 - 02/2010
2	Hypertension (High Blood Pressure) 04/2015 - 12/2007
2	Burns 02/2013 - 10/2011
2	Hernia (Hernias) 09/2012 - 08/2012
2	End Stage Liver Disease 04/2012 - 02/2004
2	Anastomotic Leak 07/2011 - 08/2006
2	Mycoses (Diseases, Fungus) 02/2009 - 01/2005
2	Liver Diseases (Liver Disease) 02/2009 - 12/2007
2	Renal Insufficiency (Renal Failure) 12/2007 - 07/2005
1	Clostridium Infections 11/2022
1	Dysbiosis 11/2022
1	Suppuration 01/2021

Drug/Important Bio-Agent (IBA)

41	Anti-Bacterial Agents (Antibiotics)IBA 11/2022 - 01/2002
8	Vancomycin FDA LinkGeneric 12/2016 - 08/2008
6	CytokinesIBA 01/2021 - 01/2005
6	Proteins (Proteins, Gene)FDA Link 01/2019 - 02/2004
5	Pharmaceutical PreparationsIBA 08/2017 - 01/2002
4	Estradiol (Delestrogen)FDA LinkGeneric 04/2011 - 01/2008
3	Carbapenems (Carbapenem Antibiotics)IBA 12/2015 - 04/2010
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2014 - 05/2010
3	Interleukin-2 (IL2)IBA 05/2014 - 05/2010
3	SteroidsIBA 02/2013 - 02/2008
3	Estrogens (Estrogen)FDA Link 03/2008 - 01/2008
2	InterferonsIBA 01/2019 - 05/2014
2	Interleukin-6 (Interleukin 6)IBA 07/2018 - 05/2010
2	Adrenal Cortex Hormones (Corticosteroids)IBA 08/2017 - 02/2009
2	chlorambucil-docosahexaenoic acid conjugateIBA 08/2017 - 10/2010
2	Tazobactam Drug Combination Piperacillin (Zosyn)FDA LinkGeneric 02/2016 - 04/2008
2	AminoglycosidesIBA 12/2015 - 01/2002
2	Indicators and Reagents (Reagents)IBA 11/2015 - 01/2002
2	Clindamycin (Cleocin)FDA LinkGeneric 10/2015 - 01/2010
2	SodiumIBA 10/2015 - 04/2012
2	Anti-Infective Agents (Microbicides)IBA 08/2015 - 10/2003
2	Hemoglobins (Hemoglobin)IBA 04/2015 - 08/2014
2	ChlorhexidineIBA 10/2014 - 10/2009
2	SolutionsIBA 08/2014 - 10/2009
2	Interleukin-8 (Interleukin 8)IBA 05/2014 - 05/2010
2	Linezolid (Zyvox)FDA Link 11/2013 - 08/2008
2	Heparin (Liquaemin)FDA LinkGeneric 06/2011 - 04/2011
2	Metronidazole (Metric)FDA LinkGeneric 10/2010 - 04/2010
2	Gonadal Steroid Hormones (Sex Hormones)IBA 03/2008 - 01/2008
2	Glutamine (L-Glutamine)FDA Link 02/2006 - 11/2005
1	BilirubinIBA 12/2021
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2021
1	Cefazolin (Ancef)FDA LinkGeneric 01/2021
1	Arachidonic Acid (Vitamin F)IBA 12/2020
1	C-Reactive ProteinIBA 12/2020
1	Adenosine Diphosphate (ADP)IBA 12/2020
1	Ferritins (Ferritin)IBA 12/2020

Therapy/Procedure

43	Therapeutics 01/2022 - 01/2002
18	Length of Stay 11/2022 - 01/2002
12	Critical Care (Surgical Intensive Care) 03/2021 - 09/2003
8	Liver Transplantation 04/2014 - 09/2004
6	Catheters 02/2016 - 04/2003
5	Blood Transfusion (Blood Transfusions) 12/2021 - 07/2002
5	Artificial Respiration (Mechanical Ventilation) 12/2021 - 12/2007
5	Renal Dialysis (Hemodialysis) 02/2016 - 12/2007
5	Transplantation 06/2014 - 01/2003
4	Operative Surgical Procedures 12/2021 - 07/2011
4	Gastrostomy 12/2019 - 11/2005
4	Duration of Therapy 08/2015 - 01/2002
3	Antibiotic Prophylaxis 01/2022 - 11/2018
3	Ligation 09/2021 - 01/2017
3	Enteral Nutrition (Feeding, Tube) 12/2019 - 02/2006
3	Mechanical Ventilators (Ventilator) 02/2012 - 09/2004
2	Tracheostomy 01/2021 - 11/2008
2	Debridement 10/2015 - 01/2008
2	Urinary Catheters 02/2013 - 06/2011
2	Herniorrhaphy 09/2012 - 02/2008
1	Pancreatectomy 12/2021
1	Pancreaticojejunostomy 12/2021
1	Pancreaticoduodenectomy 12/2021
1	Splenectomy 01/2021